Endocrine Abstracts

Objective: Maternal and female fetal virilization is subject to exaggerating androgen secretion of pregnancy luteomas which is associated with the protective capacity of placenta safeguard against hormone conversion and presents with variable extent of female pesudohermapharotidism as exposure in critical gestational stage.Patient(s): A nulligravida woman suffering from bilateral hydronephrosis and recurrent acute pyelonephritis caused by bilateral solid...

A 66-year-old woman had no history of systemic diseases. She had developed watery diarrhea for 4 months initially, without abdominal pain, fever, any aggravating or relieving factor. She visited gastroenterologist, and colonoscopy showed only mixed hemorrhoid. Irritable bowel syndrome was impressed then. Thus, anti-spasmodics and anti-diarrheals were prescribed. However, diarrhea persisted for 1 year, and body weight loss of 7 kg occurred during this period of time. She later ...

Klinefelter syndrome (47XXY male) (KS) is the most common sex chromosome disorder in men. The phenotype is diverse including: infertility, hypogonadism, impaired cognition, behavior disorders, increased autoimmunity and osteopenia. We have studied osteopenia, learning dysfunction, germ cell loss, and testosterone deficiency in 41 XXY mice bred by two separate methods. We have characterized the germ cell loss by apoptosis and germ cell migration as the mice progress from day 1 ...